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Dosing & Timing Chart

EMEA ICG Dosing for Cholecystectomy (Adult)

Indocyanine green (ICG) fluorescence imaging is widely used in cholecystectomy to enhance visualization of the biliary anatomy and support safe dissection. By enabling real-time identification of structures such as the cystic duct and common bile duct, this technique helps reduce the risk of bile duct injury—one of the most serious complications of the procedure.

In the EMEA region, standardized dosing and timing protocols help ensure consistent fluorescence imaging, improving intraoperative navigation and surgical safety.

Tissue identification

Region of interest

Bile Ducts

Dose

5 mg Or 0.0119 mg/kg

Route

I.V.*

Injection time

3 hr before surgery Or 1 hr before surgery

First ICG detection

Beginning of surgery

ICG Duration

Remains visible during procedure

Camera requirements

Laparoscope, NIR light source camera

References  (full ref details at end of this guide doc)

9. 2017, Boogerd et al.,
10. 2023, Baldari et al.,

*Saline flush (10mL) recommended post I.V. administration of Verdye™ (ICG) Injection
Note: dose may need to be adjusted to take into account differences in the Near Infra-Red (NIR) camera system being used

Bibliography
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