Skip to main content

ICG Dosing and Timing for Breast Cancer Surgery

  • Intro:

    Indocyanine green (ICG) fluorescence imaging is increasingly used in breast cancer surgery to visualize lymphatic drainage, identify sentinel lymph nodes, and assess tissue perfusion during reconstruction. Proper dosing and timing of ICG administration are essential to achieve optimal near-infrared fluorescence imaging during the procedure.

    This dosing and timing chart provides practical guidance for ICG use in breast cancer surgery, including recommended injection techniques, dosage ranges, and expected fluorescence detection times for sentinel lymph node mapping and breast reconstruction perfusion assessment.

  • Sección:
    • Title: Dosing & Timing Chart, Tabla:
      • Columna1:

        Purpose:

        , Contenido:

        Visualize lymphatic drainage & sentinel lymph node

      • Columna1:

        Injection Type: 

        , Contenido:

        Other

      • Columna1:

        Description:

        , Contenido:

        Dye administration should be subcutaneous into periareolar region of each quadrant.

      • Columna1:

        Dilution (25 mg in 10 mL of sterile water - 2.5mg/mL): 

        , Contenido:

        Yes

      • Columna1:

        Requires Flush with Sterile Water: 

        , Contenido:

        No

      • Columna1:

        Proposed Dosage: 

        , Contenido:

        1 mL

      • Columna1:

        Injection Time: 

        , Contenido:

        At start of procedure.

      • Columna1:

        First Indocyanine Green Detection: 

        , Contenido:

        Five to 10 minutes after administration

      • Columna1:

        Indocyanine Green Duration: 

        , Contenido:

        Stable during surgery. Slowly diffuses through lymphatics

      • Columna1:

        Camera Requirements (handheld device, laparoscope or both): 

        , Contenido:

        Handheld

      • Columna1:

        Tips & Tricks: 

        , Contenido:

        Total 4 mL (1 mL per periareolar quadrant). Gentle, circular motion massaging can be performed to distribute dye.

ICG Dosing and Timing for Breast Reconstruction

  • Intro:

    Indocyanine green (ICG) fluorescence imaging is widely used in breast reconstruction to assess perfusion of mastectomy skin flaps and support intraoperative decision-making. Near-infrared fluorescence angiography allows surgeons to visualize real-time blood flow and identify areas at risk of ischemia during reconstructive procedures.

    This dosing and timing chart outlines recommended ICG administration for breast reconstruction, including intravenous injection protocols, dosage guidance, and expected fluorescence detection times. These parameters help optimize intraoperative perfusion assessment and improve surgical outcomes during reconstructive breast surgery.

  • Sección:
    • Title: Dosing & Timing Chart, Tabla:
      • Columna1:

        Purpose:

        , Contenido:

        Mastectomy skin flaps perfusion

      • Columna1:

        Injection Type: 

        , Contenido:

        Intravenous

      • Columna1:

        Dilution (25 mg in 10 mL of sterile water - 2.5mg/mL): 

        , Contenido:

        Yes

      • Columna1:

        Requires Flush with Sterile Water: 

        , Contenido:

        Yes

      • Columna1:

        Proposed Dosage: 

        , Contenido:

        1 mL

      • Columna1:

        Injection Time: 

        , Contenido:

        During skin flap manipulation and reconstruction.

      • Columna1:

        First Indocyanine Green Detection: 

        , Contenido:

        30–60 seconds after administration

      • Columna1:

        Indocyanine Green Duration: 

        , Contenido:

        60 s–3 mins

      • Columna1:

        Camera Requirements (handheld device, laparoscope or both): 

        , Contenido:

        Handheld

      • Columna1:

        Tips & Tricks: 

        , Contenido:

        Adjunct to clinical assessment and surgical symmetry.

Indocyanine Green Is a Safe and Effective Alternative to Radioisotope in Breast Cancer Sentinel Lymph Node Biopsy regardless of Patient Body Mass Index

  • Título completo del paper: Indocyanine Green Is a Safe and Effective Alternative to Radioisotope in Breast Cancer Sentinel Lymph Node Biopsy regardless of Patient Body Mass Index
  • Autores: Samantha Nga, Vassilis Pitsinisa, Emad H. Elseedawya, Douglas Browna, Alessio Vincia, Benjamin A. Jonesa, E. Jane Macaskilla
  • Fecha de publicacion: 2024-11-21
  • doi: https://doi.org/10.1159/000528155

Oncological outcomes and locoregional recurrence after fluorescence guided surgery for axillary staging in early breast cancer: A single UK center experience

  • Título completo del paper: Oncological outcomes and locoregional recurrence after fluorescence guided surgery for axillary staging in early breast cancer: A single UK center experience
  • Autores: Rahul Kanitkar, Vassilis Pitsinis, Bushra Riaz, Alessio Vinci, Fiona Hogg, Lee B. Jordan
  • Fecha de publicacion: 2025-04-02
  • doi: https://doi.org/10.1016/j.ctarc.2025.100922

Identificacion de Ganglio Centinela en Cirugía de Mama y Melanoma con Fluorescencia

  • Thumbnail 512x288:
  • Título del video: Identificacion de Ganglio Centinela en Cirugía de Mama y Melanoma con Fluorescencia
  • Chapter: LATAM CHAPTER
  • Speakers: Diego Sinagra
  • Moderators: Fernando Dip
  • Youtube/Vimeo link: https://vimeo.com/915124618?share=copy
  • Date: 2024-02-20
Identificacion de Ganglio Centinela en Cirugía de Mama y Melanoma con Fluorescencia LATAM CHAPTER Diego Sinagra Fernando Dip 

Use of Fluorescence in Oncoplastic Surgery

  • Thumbnail 512x288:
  • Título del video: Use of Fluorescence in Oncoplastic Surgery
  • Chapter: LATAM CHAPTER
  • Speakers: Jacqueline Richa and Gabriel del Corral
  • Moderators: Alberto Rancati
  • Youtube/Vimeo link: https://vimeo.com/873862413?share=copy
  • Date: 2023-10-11
Use of Fluorescence in Oncoplastic Surgery LATAM CHAPTER Jacqueline Richa and Gabriel del Corral Alberto Rancati    

Uso de fluorescencia en cirugía oncoplástica

  • Thumbnail 512x288:
  • Título del video: Uso de fluorescencia en cirugía oncoplástica
  • Chapter: LATAM CHAPTER
  • Speakers: Jacqueline Richa and Gabriel del Corral
  • Moderators: Alberto Rancati
  • Youtube/Vimeo link: https://vimeo.com/873858218?share=copy
  • Date: 2023-10-11
Uso de fluorescencia en cirugía oncoplástica Jacqueline Richa and Gabriel del Corral Alberto Rancati LATAM CHAPTER

Sentinel Node in Breast Cancer and Melanoma (ENG)

  • Thumbnail 512x288:
  • Título del video: Sentinel Node in Breast Cancer and Melanoma (ENG)
  • Chapter: LATAM CHAPTER
  • Speakers: Moises Cukier
  • Moderators: Natasha Loría Terwes and Ana Carrasquilla
  • Youtube/Vimeo link: https://vimeo.com/854525057?share=copy
  • Date: 2023-08-10
Sentinel Node in Breast Cancer and Melanoma (ENG) LATAM CHAPTER Moises Cukier Natasha Loría Terwes and Ana Carrasquilla

Exploring the Applications of Indocyanine Green in Robot-Assisted Urological Surgery: A Comprehensive Review of Fluorescence-Guided Techniques

  • Título completo del paper: Oncological outcomes and locoregional recurrence after fluorescence guided surgery for axillary staging in early breast cancer: A single UK center experience
  • Autores: Rahul Kanitkar, Vassilis Pitsinis, Bushra Riaz, Alessio Vinci, Fiona Hogg , Lee B. Jordan
  • Fecha de publicacion: 2023-06-11
  • doi: https://doi.org/10.1016/j.ctarc.2025.100922