Indocyanine green (ICG) fluorescence imaging is increasingly used in breast cancer surgery to visualize lymphatic drainage, identify sentinel lymph nodes, and assess tissue perfusion during reconstruction. Proper dosing and timing of ICG administration are essential to achieve optimal near-infrared fluorescence imaging during the procedure.
This dosing and timing chart provides practical guidance for ICG use in breast cancer surgery, including recommended injection techniques, dosage ranges, and expected fluorescence detection times for sentinel lymph node mapping and breast reconstruction perfusion assessment.
Indocyanine green (ICG) fluorescence imaging is widely used in breast reconstruction to assess perfusion of mastectomy skin flaps and support intraoperative decision-making. Near-infrared fluorescence angiography allows surgeons to visualize real-time blood flow and identify areas at risk of ischemia during reconstructive procedures.
This dosing and timing chart outlines recommended ICG administration for breast reconstruction, including intravenous injection protocols, dosage guidance, and expected fluorescence detection times. These parameters help optimize intraoperative perfusion assessment and improve surgical outcomes during reconstructive breast surgery.
Sección:
Title: Dosing & Timing Chart, Tabla:
Columna1:
Purpose:
, Contenido:
Mastectomy skin flaps perfusion
Columna1:
Injection Type:
, Contenido:
Intravenous
Columna1:
Dilution (25 mg in 10 mL of sterile water - 2.5mg/mL):
, Contenido:
Yes
Columna1:
Requires Flush with Sterile Water:
, Contenido:
Yes
Columna1:
Proposed Dosage:
, Contenido:
1 mL
Columna1:
Injection Time:
, Contenido:
During skin flap manipulation and reconstruction.
Columna1:
First Indocyanine Green Detection:
, Contenido:
30–60 seconds after administration
Columna1:
Indocyanine Green Duration:
, Contenido:
60 s–3 mins
Columna1:
Camera Requirements (handheld device, laparoscope or both):
, Contenido:
Handheld
Columna1:
Tips & Tricks:
, Contenido:
Adjunct to clinical assessment and surgical symmetry.
Título completo del paper: Indocyanine Green Is a Safe and Effective Alternative to Radioisotope in Breast Cancer Sentinel Lymph Node Biopsy regardless of Patient Body Mass Index
Autores: Samantha Nga, Vassilis Pitsinisa, Emad H. Elseedawya, Douglas Browna, Alessio Vincia, Benjamin A. Jonesa, E. Jane Macaskilla
Título completo del paper: Oncological outcomes and locoregional recurrence after fluorescence guided surgery for axillary staging in early breast cancer: A single UK center experience
Autores: Rahul Kanitkar, Vassilis Pitsinis, Bushra Riaz, Alessio Vinci, Fiona Hogg, Lee B. Jordan
Título completo del paper: Oncological outcomes and locoregional recurrence after fluorescence guided surgery for axillary staging in early breast cancer: A single UK center experience
Autores: Rahul Kanitkar, Vassilis Pitsinis, Bushra Riaz, Alessio Vinci, Fiona Hogg , Lee B. Jordan