Indocyanine green (ICG) fluorescence imaging is widely used in liver cancer surgery to improve visualization of hepatic tumors and support accurate intraoperative localization. Using near-infrared fluorescence imaging, surgeons can detect liver lesions, identify tumor margins, and guide precise hepatic resections.
This dosing and timing chart provides guidance on recommended ICG administration for liver cancer procedures, including intravenous dosing protocols, timing of injection before surgery, and expected fluorescence detection to optimize tumor visualization during fluorescence-guided hepatic surgery.
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Title: Dosing & Timing Chart, Tabla:
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Purpose:
, Contenido:
Visualization of primary & metastatic liver tumors
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Injection Type:
, Contenido:
Intravenous
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Dilution (25 mg in 10 mL of sterile water - 2.5mg/mL):
, Contenido:
Yes
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Requires Flush with Sterile Water:
, Contenido:
Yes
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Proposed Dosage:
, Contenido:
0.5 mg/kg
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Injection Time:
, Contenido:
7 days preoperatively
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First Indocyanine Green Detection:
, Contenido:
Real time during hepatectomy
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Indocyanine Green Duration:
, Contenido:
Remains stable during surgery
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Camera Requirements (handheld device, laparoscope or both):
, Contenido:
Both
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Tips & Tricks:
, Contenido:
Hepatocellular carcinoma shows cancerous fluorescence signals. Metastatic tumors show rim fluorescence signals.
Indocyanine green (ICG) fluorescence imaging is widely used in hepatic surgery to visualize liver segments and guide precise anatomical resections. Using near-infrared fluorescence imaging, surgeons can identify segmental boundaries and vascular territories in real time, improving accuracy during liver segmentation and hepatectomy procedures.
This dosing and timing chart provides guidance on recommended ICG administration for liver segmentation techniques, including intravenous injection protocols, dosage considerations, and fluorescence detection timing to optimize visualization of hepatic segments during fluorescence-guided liver surgery.
Sección:
Title: Dosing & Timing Chart, Contenido:
*For 0.1 and 0.2 mL doses, utilize an insulin syringe to draw/administer volumen.
, Tabla:
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Purpose:
, Contenido:
Visualize liver segments
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Injection Type:
, Contenido:
Other
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Description:
, Contenido:
Positive staining technique: inject directly into the portal branch.
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Dilution (25 mg in 10 mL of sterile water - 2.5mg/mL):
, Contenido:
Yes
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Requires Flush with Sterile Water:
, Contenido:
No
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Proposed Dosage:
, Contenido:
0.1 mL*
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Injection Time:
, Contenido:
Prior to hepatic dissection
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First Indocyanine Green Detection:
, Contenido:
Several seconds after administration
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Indocyanine Green Duration:
, Contenido:
Remains stable during surgery
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Camera Requirements (handheld device, laparoscope or both):
, Contenido:
Both
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Tips & Tricks:
, Contenido:
Positive staining should be performed under ultrasound-guided portal branch puncture.
Title: Dosing & Timing Chart, Tabla:
Columna1:
Purpose:
, Contenido:
Visualize liver segments
Columna1:
Injection Type:
, Contenido:
Intravenous
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Description:
, Contenido:
Negative staining technique: Administer via peripheral intravenous access
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Dilution (25 mg in 10 mL of sterile water - 2.5mg/mL):
, Contenido:
Yes
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Requires Flush with Sterile Water:
, Contenido:
Yes
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Proposed Dosage:
, Contenido:
1 mL
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Injection Time:
, Contenido:
After portal pedicle closure
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First Indocyanine Green Detection:
, Contenido:
Several seconds after administration
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Indocyanine Green Duration:
, Contenido:
Remains stable during surgery
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Camera Requirements (handheld device, laparoscope or both):
