Título del video: Vessel Skeletonisation in Lateral Pelvic Lymph Node Dissection for Patients with Anomalous Anatomy after Neoadjuvant Treatment for Locally Advanced Rectal Cancer
Speakers: G Karagiannidis, MD, L Algazawi, MD, R Labinoti, MD, Arshad Malik, MD
Descripción: This video demonstrates vessel skeletonisation during lateral pelvic lymph node dissection in patients with complex or anomalous anatomy following neoadjuvant therapy for locally advanced rectal cancer. The technique highlights precise vascular dissection and careful anatomical identification to optimize oncologic outcomes while minimizing complications.
Indocyanine green (ICG) fluorescence imaging is widely used in breast cancer surgery for sentinel lymph node mapping and lymphatic visualization. This technique enables accurate identification of nodal drainage pathways, supporting precise staging while reducing the need for extensive lymph node dissection.
Clinical evidence shows that ICG provides high detection rates and can be comparable or superior to conventional methods such as blue dye or radioisotopes, while avoiding their limitations.
In the EMEA region, standardized dosing and timing protocols help ensure consistent fluorescence imaging and improve intraoperative decision-making in breast cancer surgery.
Sección:
Tabla:
Columna1:
Region of interest
, Contenido:
Sentinel Lymph Node (SLN)
Columna1:
Dose
, Contenido:
2 mL (2.5 mg/mL) (2-4 injection sites)
Columna1:
Route
, Contenido:
I.D. into lateral areolar region
Columna1:
Injection time
, Contenido:
After induction of anaesthesia with subsequent breast massage
Columna1:
First ICG detection
, Contenido:
Beginning of surgery
Columna1:
ICG Duration
, Contenido:
Remains visible during procedure as it diffuses slowly via lymphatics
Columna1:
Camera requirements
, Contenido:
Open procedure, NIR light source camera
Columna1:
References (full ref details at end of this guide doc)
Indocyanine green (ICG) fluorescence imaging is widely used in cervical cancer surgery for sentinel lymph node mapping and lymphatic visualization. This technique enables accurate identification of nodal drainage pathways, reducing the need for extensive lymphadenectomy and associated morbidity.
In the EMEA region, standardized dosing and timing protocols help ensure consistent fluorescence imaging, improving detection rates and supporting intraoperative decision-making in gynecologic oncology.
Sección:
Tabla:
Columna1:
Region of interest
, Contenido:
Sentinel Lymph Node (SLN)
Columna1:
Dose
, Contenido:
0.25 mL (2.5 mg/mL)
Columna1:
Route
, Contenido:
Submucosal peritumorally at 2,4, 8 and 10 o’clock
Columna1:
Injection time
, Contenido:
Onset of surgery
Columna1:
First ICG detection
, Contenido:
After 10 min
Columna1:
ICG Duration
, Contenido:
Remains visible during procedure as it diffuses slowly via lymphatics
Columna1:
Camera requirements
, Contenido:
Laparoscope, NIR light source camera
Columna1:
References (full ref details at end of this guide doc)
Indocyanine green (ICG) fluorescence imaging is increasingly used in melanoma surgery for sentinel lymph node mapping and lymphatic visualization. Sentinel lymph node biopsy is a critical step in staging melanoma, allowing accurate assessment of nodal involvement and guiding further treatment decisions.
ICG-based near-infrared imaging enables real-time visualization of lymphatic drainage pathways and has demonstrated comparable detection rates to conventional techniques such as radiocolloid and blue dye, while improving intraoperative guidance.
In the EMEA region, standardized dosing and timing protocols help ensure consistent fluorescence imaging and support precise, minimally invasive surgical approaches in melanoma management.
Sección:
Tabla:
Columna1:
Region of interest
, Contenido:
SLN
Columna1:
Dose
, Contenido:
Head & Neck 0.1-0.3 mL Elsewhere 0.2-0.3 mL (2.5 mg/mL)
Columna1:
Route
, Contenido:
Intra-dermal
Columna1:
Injection time
, Contenido:
Intra-operatively
Columna1:
First ICG detection
, Contenido:
Beginning of assessment
Columna1:
ICG Duration
, Contenido:
Remains visible during procedure
Columna1:
Camera requirements
, Contenido:
NIR light source camera
Columna1:
References (full ref details at end of this guide doc)
Indocyanine green (ICG) fluorescence imaging is increasingly used in breast cancer surgery to visualize lymphatic drainage, identify sentinel lymph nodes, and assess tissue perfusion during reconstruction. Proper dosing and timing of ICG administration are essential to achieve optimal near-infrared fluorescence imaging during the procedure.
This dosing and timing chart provides practical guidance for ICG use in breast cancer surgery, including recommended injection techniques, dosage ranges, and expected fluorescence detection times for sentinel lymph node mapping and breast reconstruction perfusion assessment.
Indocyanine green (ICG) fluorescence imaging is widely used in breast reconstruction to assess perfusion of mastectomy skin flaps and support intraoperative decision-making. Near-infrared fluorescence angiography allows surgeons to visualize real-time blood flow and identify areas at risk of ischemia during reconstructive procedures.
This dosing and timing chart outlines recommended ICG administration for breast reconstruction, including intravenous injection protocols, dosage guidance, and expected fluorescence detection times. These parameters help optimize intraoperative perfusion assessment and improve surgical outcomes during reconstructive breast surgery.
Sección:
Title: Dosing & Timing Chart, Tabla:
Columna1:
Purpose:
, Contenido:
Mastectomy skin flaps perfusion
Columna1:
Injection Type:
, Contenido:
Intravenous
Columna1:
Dilution (25 mg in 10 mL of sterile water - 2.5mg/mL):
, Contenido:
Yes
Columna1:
Requires Flush with Sterile Water:
, Contenido:
Yes
Columna1:
Proposed Dosage:
, Contenido:
1 mL
Columna1:
Injection Time:
, Contenido:
During skin flap manipulation and reconstruction.
Columna1:
First Indocyanine Green Detection:
, Contenido:
30–60 seconds after administration
Columna1:
Indocyanine Green Duration:
, Contenido:
60 s–3 mins
Columna1:
Camera Requirements (handheld device, laparoscope or both):
, Contenido:
Handheld
Columna1:
Tips & Tricks:
, Contenido:
Adjunct to clinical assessment and surgical symmetry.
Indocyanine green (ICG) fluorescence imaging is widely used in gynecologic oncology to visualize lymphatic drainage and identify sentinel lymph nodes during cervical and endometrial cancer surgery. Proper dosing, injection site, and timing of ICG administration are critical to achieve reliable near-infrared fluorescence imaging and accurate lymphatic mapping.
This dosing guide outlines recommended ICG administration techniques for cervical and endometrial cancer procedures, including injection into the cervical submucosa and deep stromal tissue, dosage per quadrant, and expected fluorescence detection during sentinel lymph node mapping.
Administration of the dye should be performed at the level of the cervical submucosa, deep into the stroma. The dye should be distributed into 4 cervical quadrants.
Columna1:
Dilution (25 mg in 10 mL of sterile water - 2.5mg/mL):
, Contenido:
Yes
Columna1:
Requires Flush with Sterile Water:
, Contenido:
No
Columna1:
Proposed Dosage:
, Contenido:
1 mL
Columna1:
Injection Time:
, Contenido:
Prior to dissection & insertion of uterine manipulator
Columna1:
First Indocyanine Green Detection:
, Contenido:
At start of procedure
Columna1:
Indocyanine Green Duration:
, Contenido:
Stable during surgery. Slowly diffuses through lymphatics
Columna1:
Camera Requirements (handheld device, laparoscope or both):
Indocyanine green (ICG) fluorescence imaging is used in melanoma surgery to visualize lymphatic drainage and support sentinel lymph node mapping. With near-infrared fluorescence imaging, surgeons can track lymphatic pathways in real time and identify sentinel lymph nodes to improve staging accuracy and surgical precision.
This dosing chart outlines recommended ICG administration for melanoma procedures, including peritumoral injection techniques, dosage guidance, and expected fluorescence detection timing to optimize lymphatic mapping during fluorescence-guided melanoma surgery.
Sección:
Title: Dosing & Timing Chart, Contenido:
*For 0.1 and 0.2 mL doses, utilize an insulin syringe to draw/administer volumen.
, Tabla:
Columna1:
Purpose:
, Contenido:
Sentinel lymph node identification
Columna1:
Injection Type:
, Contenido:
Other
Columna1:
Description:
, Contenido:
Administration should be intradermal, surrounding the area of interest.
Columna1:
Dilution (25 mg in 10 mL of sterile water - 2.5mg/mL):
, Contenido:
Yes
Columna1:
Requires Flush with Sterile Water:
, Contenido:
No
Columna1:
Proposed Dosage:
, Contenido:
0.2 mL*
Columna1:
Injection Time:
, Contenido:
Five min prior to manipulation of skin site
Columna1:
First Indocyanine Green Detection:
, Contenido:
Five to 10 minutes after administration
Columna1:
Indocyanine Green Duration:
, Contenido:
Stable during surgery. Slowly diffuses through lymphatics
Columna1:
Camera Requirements (handheld device, laparoscope or both):
, Contenido:
Handheld
Columna1:
Tips & Tricks:
, Contenido:
Dye administration should be performed prior to local anesthesia administration
Indocyanine green (ICG) fluorescence imaging is increasingly used in vulvar cancer surgery to visualize lymphatic drainage and identify sentinel lymph nodes. With near-infrared fluorescence imaging, surgeons can track lymphatic pathways in real time, improving sentinel lymph node detection and supporting more precise oncologic staging.
This dosing chart provides guidance on recommended ICG administration for vulvar cancer procedures, including peritumoral injection techniques, dosage per injection site, and expected fluorescence detection timing to optimize sentinel lymph node mapping during fluorescence-guided surgery.
Título del video: Use of ICG Near-Infrared Fluorescent Dye in Confirming Successful Radiotracer Mapping and Sentinel Lymph Node Biopsy in Patients with Cutaneous Melanoma
Título completo del paper: Indocyanine Green Is a Safe and Effective Alternative to Radioisotope in Breast Cancer Sentinel Lymph Node Biopsy regardless of Patient Body Mass Index
Autores: Samantha Nga, Vassilis Pitsinisa, Emad H. Elseedawya, Douglas Browna, Alessio Vincia, Benjamin A. Jonesa, E. Jane Macaskilla
Título completo del paper: Oncological outcomes and locoregional recurrence after fluorescence guided surgery for axillary staging in early breast cancer: A single UK center experience
Autores: Rahul Kanitkar, Vassilis Pitsinis, Bushra Riaz, Alessio Vinci, Fiona Hogg, Lee B. Jordan
Título completo del paper: Results of a Prospective Randomized Multicenter Study Comparing Indocyanine Green (ICG) Fluorescence Combined with a Standard Tracer Versus ICG Alone for Sentinel Lymph Node Biopsy in Early Breast Cancer: The INFLUENCE Trial
