• Columna1:

  Region of interest

  , Contenido:

  Skin and autologous flap 

• Columna1:

  Dose

  , Contenido:

  7.5 mg bolus

• Columna1:

  Route

  , Contenido:

  I.V.*

• Columna1:

  Injection time

  , Contenido:

  Intraoperatively

• Columna1:

  First ICG detection

  , Contenido:

  60-120 sec

• Columna1:

  ICG Duration

  , Contenido:

  2-4 min

• Columna1:

  Camera requirements

  , Contenido:

  NIR light source camera

• Columna1:

  References  (full ref details at end of this guide doc)

  , Contenido:

  1. 2018, Alstrup et al.,

• Columna1:

  Purpose:

  , Contenido:

  Visualize lymphatic drainage & sentinel lymph node

• Columna1:

  Injection Type: 

  , Contenido:

  Other

• Columna1:

  Description:

  , Contenido:

  Dye administration should be subcutaneous into periareolar region of each quadrant.

• Columna1:

  Dilution (25 mg in 10 mL of sterile water - 2.5mg/mL): 

  , Contenido:

  Yes

• Columna1:

  Requires Flush with Sterile Water: 

  , Contenido:

  No

• Columna1:

  Proposed Dosage: 

  , Contenido:

  1 mL

• Columna1:

  Injection Time: 

  , Contenido:

  At start of procedure.

• Columna1:

  First Indocyanine Green Detection: 

  , Contenido:

  Five to 10 minutes after administration

• Columna1:

  Indocyanine Green Duration: 

  , Contenido:

  Stable during surgery. Slowly diffuses through lymphatics

• Columna1:

  Camera Requirements (handheld device, laparoscope or both): 

  , Contenido:

  Handheld

• Columna1:

  Tips & Tricks: 

  , Contenido:

  Total 4 mL (1 mL per periareolar quadrant). Gentle, circular motion massaging can be performed to distribute dye.

• Columna1:

  Purpose:

  , Contenido:

  Mastectomy skin flaps perfusion

• Columna1:

  Injection Type: 

  , Contenido:

  Intravenous

• Columna1:

  Dilution (25 mg in 10 mL of sterile water - 2.5mg/mL): 

  , Contenido:

  Yes

• Columna1:

  Requires Flush with Sterile Water: 

  , Contenido:

  Yes

• Columna1:

  Proposed Dosage: 

  , Contenido:

  1 mL

• Columna1:

  Injection Time: 

  , Contenido:

  During skin flap manipulation and reconstruction.

• Columna1:

  First Indocyanine Green Detection: 

  , Contenido:

  30–60 seconds after administration

• Columna1:

  Indocyanine Green Duration: 

  , Contenido:

  60 s–3 mins

• Columna1:

  Camera Requirements (handheld device, laparoscope or both): 

  , Contenido:

  Handheld

• Columna1:

  Tips & Tricks: 

  , Contenido:

  Adjunct to clinical assessment and surgical symmetry.

*For 0.1 and 0.2 mL doses, utilize an insulin syringe to draw/administer volumen.

• Columna1:

  Purpose:

  , Contenido:

  Lymph vessel assessment

• Columna1:

  Injection Type: 

  , Contenido:

  Other

• Columna1:

  Description: 

  , Contenido:

  Administration should be subcutaneous into bilateral interdigit hand or foot.

• Columna1:

  Dilution (25 mg in 10 mL of sterile water - 2.5mg/mL): 

  , Contenido:

  Yes

• Columna1:

  Requires Flush with Sterile Water: 

  , Contenido:

  No

• Columna1:

  Proposed Dosage: 

  , Contenido:

  0.1 mL*

• Columna1:

  Injection Time: 

  , Contenido:

  At time of lymph vessel evaluation

• Columna1:

  First Indocyanine Green Detection: 

  , Contenido:

  Minutes after administration

• Columna1:

  Indocyanine Green Duration: 

  , Contenido:

  Hours

• Columna1:

  Camera Requirements (handheld device, laparoscope or both): 

  , Contenido:

  Handheld

• Columna1:

  Tips & Tricks: 

  , Contenido:

  Gentle, circular motion massaging can be performed to distribute dye.